United States securities and exchange commission logo February 9, 2021 James Thompson Chief Executive Officer SPYR, Inc. 8547 E. Arapahoe Rd., #J527 Greenwood Village, CO 80112 Re: SPYR, Inc. Registration Statement on Form S-1 Filed February 3, 2021 File No. 333-252683 Dear Mr. Thompson: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Nicholas Lamparski at (202) 551-4695 with any questions. Sincerely, Division of Corporation Finance Office of Trade & Services cc: Tad Mailander